Biology and Biochemistry of Cancer

Cancer Incidence, Mortality Rate, Effect of Age, Etiology (Cause)

• 1. List and describe the events of cancer progression.


• 2. The properties of cancer can be studied by what methods?


• 3. Compare and contrast properties of neoplastic cells versus normal cells.


• 4. Define cancer incidence and cancer mortality.


• 5. What is the relationship between age and cancer?


• 6. What cancers are the most prominent causes of death in men? In women?


• 7. Is the incidence of death from cancer rising or decreasing?


• 8. What is the most likely general cause of cancers, worldwide?


• 9. Define protooncogenes and tumor suppressor genes. What are their normal functions?


• 10. Name the types of mutations involved in altering these genes.


• 11. Name two tumor suppressor genes.


• 12. Describe how cancer can occur by genetic change


• 13. List the three classes of agents to cause cancer. For each class, describe the ways in which cancer can be caused.


• 14. What are some factors that can increase the incidence of tumors?


• 15. Name a specific type of cancer and the risk factors for that type.


• 16. What are some ways in which cancer can be managed?

17. What are the risk factors for lung cancer? Breast cancer? Uterine cancer? Colon cancer? Oral cancer?