Diseases of the Breast

Breast Enlargement, Fat Necrosis, Fibrocystic Disease, Breast Cancer

1. 1. Describe the anatomic features of the female breast.


2. 2. What causes the enlargement of breast during pregnancy?


3. 3. List some of the congenital diseases of the breast.


4. 4. Describe the histologic features of acute mastitis.


5. 5. Describe the histologic features of fat necrosis.


6. 6. What is the most common disease of the female breast?


7. 7. What breast lesions are amenable to diagnosis by fine needle aspiration?


8. 8. What are the pathologic findings seen in fibrocystic disease of the breast?


9. 9. What is the relative risk of cancer in fibrocystic disease of the breast?


10. 10. What is the clinical presentation of fibrocystic disease of the breast?


11. 11. What is the typical clinical presentation of a fibroadenoma?


12. 12. What are the key histologic elements of a fibroadenoma?


13. 13. What are the risk factors for breast cancer?


14. 14. What are the receptors of particular prognostic importance in breast cancer?


15. 15. Describe the role of the BRAC 1 and 2 gene mutations in breast cancer.


16. 16. What are the advantages of mammography?


17. 17. Describe palpable mass and non-palpable mass.


18. 18. What is the distribution pattern of cancers of the breast compared to benign lesions?


19. 19. What are the routes of spread of breast cancer?


20. 20. Describe the pathologic features of breast cancer. What is the most common type?


21. 21. What operations are currently performed for breast cancer?


22. 22. What chemotherapeutic agents are currently used and under what circumstances?


23. 23. What is the role of radiation for breast cancer? (When is it used?)


24. 24. What factors influence survival for breast cancer?


25. 25. What is the definition gynecomastia of the male breast? What treatment is undertaken?