Genitourinary Pathology-Kidney-Bladder-Testis-Prostate

Pathology of the Kidney, Male Genitalia, Cancer of the Prostate

• 1. Name the three pathogenic mechanisms of glomeruli disorders.


• 2. Define the clinical and laboratory findings seen in nephrotic syndrome and acute nephritis.


• 3. Compare the following diseases with respect to age, clinical syndrome of presentation and morphologic changes:


• 4. minimal change disease


• 5. focal and segmental glomerulosclerosis


• 6. membranoproliferative glomerulonephritis


• 7. membranous glomerulopathy


• 8. post infection glomerulonephritis


• 9. IgA nephropathy


• 10. Goodpasteur’s syndrome


• 11. What are two important examples of non-immunological glomerular diseases, and what are the clinical manifestations?


• 12. Name the interstitial renal diseases.


• 13. What is the most common drug that causes interstitial nephritis?


• 14. Name the tubular renal diseases.


• 15. What is the pathogenesis for acute tubular necrosis?


• 16. Which disease is characterized by inflammation of renal pelvis and interstitium due to acute bacterial infection?


• 17. Name 3 important malignant neoplasms of the kidney.


• 18. What is the cellular composition of Wilm’s tumor?


• 19. What is the histologic appearance of renal cell carcinoma?


• 20. What is the histologic appearance of transitional cell carcinoma and from what specific sites in the urinary tract are they most likely to arise?


• 21. What are the two main general categories of lesions in the testes?


• 22. Which testicular neoplasm is highly malignant, rapidly metastasizing?


• 23. Which is the most common and least aggressive testicular neoplasm?


• 24. Cystitis is characterized by what in the urinary bladder?


• 25. What tumors arise in the prostate?


• 26. Distinguish the typical clinical presentation of prostate hyperplasia from prostate carcinoma.


• 27. Describe the histologic findings hyperplasia versus carcinoma of the prostate.