Wound Healing
Non-specific wound healing (general concepts); Specific Wounds, Healing by Primary and Secondary Intention.
- 1. Describe the sequence of events in non-specific wound healing, and provide a related time table.
- 2. Define wound contraction.
- 3. Define wound strengthening.
- 4. Compare and contrast abrasion from incision/laceration.
- 5. Describe a wound with epidermal defects.
- 6. Which substances are elaborated, and by which cells (i.e., collagen types, fibronectin, etc)?
- 7. Compare temporary matrix composition vs. definitive matrix composition.
- 8. List the cells, and cell components involved in wound contraction. Provide a time frame of events.
- 9. What is the tensile strength of the wound at time points 1 week, and 3 months?
- 10. Compare the tensile strength of various collagens.
- 11. Describe the time course of healing of a sutured skin wound.
- 12. Compare the processes of primary vs. secondary intention in terms of inflammation, necrosis, cellular proliferation, and scar formation.
- 13. What are the events of healing following bone fracture?
- 14. What are the growth factors involved in wound healing?
- 15. List the local and systemic factors that interfere with wound healing.
- 16. Define pyogenic granuloma and keloid, and describe their morphologic features in histologic sections.
- 17. What is the role of matrix metalloprocesses in wound healing?
- 18. Name a few diseases and factors that interfere with healing.
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